Surgery and Photodynamic Therapy in Treating Patients With Malignant Mesothelioma
Surgery and Photodynamic Therapy in Treating Patients With Malignant Mesothelioma
Background:
Photodynamic therapy uses light and drugs that make cancer cells more sensitive to light to kill cancer cells. Combining photodynamic therapy with surgery may be an effective treatment for malignant mesothelioma. This a Phase II trial to study the effectiveness of combining photodynamic therapy with surgery in treating patients who have malignant mesothelioma.
Inclusion Criteria:
Histologically or cytologically confirmed malignant mesothelioma, including the following cell types:
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Mixed mesothelial |
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Sarcomatous |
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Stage I or II disease using the Buchart system as determined by CT scan or MRI |
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Disease confined to 1 hemithorax |
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No tumor involvement of esophagus or heart as evidenced by CT scan |
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Pericardial or diaphragmatic involvement allowed if disease is limited to the ipsilateral chest |
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N2 disease allowed if no contralateral pleural involvement |
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No adenocarcinoma or nonmesotheliomasarcoma of the chest wall |
Location/Contact Information:
New York
Roswell Park Cancer Institute,
Buffalo, New York, 14263-0001, United States;
Recruiting
Timothy M. Anderson, MD 716-845-5873
timothy.anderson@roswellpark.org
Study chairs or principal investigators
Timothy M. Anderson, MD, Study Chair
Roswell Park Cancer Institute
