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Phase II Randomized Study of Gemcitabine and Cisplatin With or Without Bevacizumab in Patients With Malignant Mesothelioma
Background: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Monoclonal antibodies such as bevacizumab can locate tumor cells and kill them without harming normal cells. It is not yet known if combination chemotherapy is more effective with or without bevacizumab in treating malignant mesothelioma. This is a Randomized phase II trial to compare the effectiveness of combination chemotherapy with or without bevacizumab in treating patients who have malignant mesothelioma.
Location/Contacts: University of Chicago Cancer Research Center Hedy L. Kindler, MD, Protocol Chair Ph: 773-702-0360; 1-888-824-0200 California Duarte City of Hope Comprehensive Cancer Center Marianna Koczywas, MD Ph: 626-359-8111 1-800-826-4673 mkocywas@coh.org Pasadena City of Hope Medical Group Mark V. McNamara, MD Ph: 626-396-2900 mmcnmara@ccsmg.com Sacramento University of California Davis Cancer Center David R. Gandara, MD Ph: 916-734-3772 dgandara@cc.ucdmc.ucdavis.edu Illinois Chicago Louis A. Weiss Memorial Hospital Gary D. Steinberg, MD Ph: 773-564-5272 University of Chicago Cancer Research Center Hedy L. Kindler, MD Ph: 773-702-0360 1-888-824-0200 Decatur Decatur Memorial Hospital Cancer Center Institute James L. Wade, MD Ph: 217-876-6603 Harvey Ingalls Memorial Hospital Mark F. Kozloff, MD Ph: 708-333-2300. Sulochana D. Yalavarthi, MD Ph: 708-915-6620 LaGrange LaGrange Memorial Hospital James E. Hannigan, MD Ph: 708-579-3418 Renee H. Jacobs, MD Ph: 708-579-3418 Maywood Loyola University Medical Center Joseph I. Clark, MD Ph: 708-327-3236 jclark@lumc.edu Kathy S. Albain, MD Ph: 708-327-3102 kalbain@lumc.edu Peoria Oncology/Hematology Associates of Central Illinois, P.C. James A. Knost, MD, FACP Ph: 309-672-5681 John W. Kugler, MD Ph: 309-671-3605 Indiana Fort Wayne Fort Wayne Medical Oncology and Hematology, Inc. David Frank Sciortino, MD Ph: 219-484-8830 Sreenivasa Rao Nattam, MD Ph: 219-484-8830 800-852-2333 ledgar@fwmoh.com South Bend CCOP-Northern Indiana CR Consortium David Allen Taber, MD Ph: 800-284-7370 Rafat H. Ansari, MD, FACP Ph: 219-234-5123 Michigan Saint Joseph Lakeland Medical Center - St. Joseph Eric Lester, MD Ph: 616-982-4963 New York New York Memorial Sloan-Kettering Cancer Center Lee M. Krug, MD Ph: 212-639-8420 Pennsylvania Philadelphia University of Pennsylvania Cancer Center James Stevenson, MD Ph: 215-662-8756 Texan Houston University of Texas - MD Anderson Cancer Center Charles Lu, MD Ph: 713-792-6363 1-800-392-1611
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